About
I am a neurosurgeon with research spanning high-density MEA recordings, single-nucleus RNA-seq, and somatic mutation mapping in pediatric epilepsy. I build clinical and experimental pipelines to bridge mechanistic insight with patient care.
Education & Training
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Pediatric Neurosurgery Fellowship Children’s Hospital of Philadelphia (UPenn) • 07/2025 – 07/2026
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Neurological Surgery Residency UCSF • 06/2018 – 06/2025
NIH R25 funding recipient 2022–24 • Best Basic Science Research 2023–25
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M.D., Yale School of Medicine 08/2013 – 05/2018
HHMI-CURE medical research fellow 2016–17
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Postbaccalaureate Premed Program Columbia University • 08/2010 – 06/2012
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B.A. English & Psychology, Cum Laude University of Missouri • 08/2004 – 06/2009
NCAA Division I Wrestling • First Team Academic All-Big XII
Selected Publications
- Multimodal evaluation of network activity and optogenetic interventions in human hippocampus. Nature Neuroscience, 2024.
- Dissociation of Broca’s Area from Broca’s Aphasia in patients undergoing surgical resections. Journal of Neurosurgery, 2022.
- Oncogenic NTRK fusion in congenital spinal cord glioblastoma: sequencing directs treatment. Lancet, 2021.
- Association of seizure spread with surgical failure in epilepsy. JAMA Neurology, 2019.
- Mechanisms of decreased cholinergic arousal in focal seizures: in vivo whole-cell recordings from the pedunculopontine tegmental nucleus. Experimental Neurology, 2019.
Peer-Reviewed Publications
- Multimodal evaluation of network activity and optogenetic interventions in human hippocampus. Nature Neuroscience, 2024.
- Amniotic membrane interposition graft for open fetal myelomeningocele repair. Operative Neurosurgery, 2025.
- Single-level laminoplasty approach to selective dorsal rhizotomy with conus localization by rapid spine MRI. Child’s Nervous System, 2024.
- Intraventricular meningioma resection and visual outcomes. Journal of Neurosurgery (Cover Article), 2023.
- Improved psychotic symptoms following resection of amygdalar low grade glioma. Journal of Neurosurgery: Case Lessons, 2022.
- Dissociation of Broca’s Area from Broca’s Aphasia in patients undergoing surgical resections. Journal of Neurosurgery, 2022.
- Xenotransplantation of porcine progenitor cells in an epileptic California sea lion (Zalophus californianus). Journal of Neurosurgery: Case Lessons, March 2022. *co-first authors.
- Oncogenic NTRK fusion in congenital spinal cord glioblastoma: sequencing directs treatment. Lancet, 2021.
- Prosopagnosia following nonlanguage dominant inferior temporal lobe low-grade glioma resection… illustrative case. Journal of Neurosurgery: Case Lessons, Sept 2021.
- Paramedian transparietal approach to a dominant hemisphere intraventricular meningioma: illustrative case. Journal of Neurosurgery: Case Lessons, Aug 2021.
- Plurihormonal Pit-1 Positive Pituitary Adenomas: a systematic review and single center series. World Neurosurgery, 2021.
- Thalamic Stimulation Improves Postictal Cortical Arousal and Behavior. Journal of Neuroscience, 2020.
- Early seizure spread and epilepsy surgery: a systematic review. Epilepsia, Oct 2020.
- Decompression of a Dorsal arachnoid web. Operative Neurosurgery, 2020.
- Pure apraxia of speech after resection based in the posterior middle frontal gyrus. Neurosurgery, 2020.
- Lesser occipital nerve damage after retrosigmoid craniotomy repaired with processed nerve allograft. Interdisciplinary Neurosurgery, 2019.
- Up and Down States of Cortical Neurons in Focal Limbic Seizures. Cerebral Cortex, 2019.
- Neocortical Epilepsy. In: Stereotactic and Functional Neurosurgery: Principles and Applications. Springer, 2019.
- Seizure-Mapping. In: Brain Mapping: Indications and Techniques. Thieme, 2019.
- Patient Safety Movement in Neurological Surgery: The Current State and Future Directions. Journal of Neurosurgery, 2019.
- Mechanisms of decreased cholinergic arousal in focal seizures: in vivo whole-cell recordings from the pedunculopontine tegmental nucleus. Experimental Neurology, 2019.
- Association of seizure spread with surgical failure in epilepsy. JAMA Neurology, 2019.
- Peduncular psychosis. BMJ Case Reports, Aug 10, 2016.
- Impaired serotonergic brainstem function during and following seizures. Journal of Neuroscience, 2016.
- Neurostimulation to improve level of consciousness in patients with epilepsy. Neurosurgical Focus, 2015.
- Decreased subcortical cholinergic arousal in focal seizures. Neuron, 2015.
- Aberrant Lymphatic Endothelial Progenitors in Lymphatic Malformation Development. PLoS ONE, 2015.
- Notch suppresses angiogenesis and progression of hepatic metastases. Cancer Research, 2015.
- Superior effectiveness of ibuprofen compared with other NSAIDs for inhibition of human prostate cancer cell growth. Cancer Chemotherapy and Pharmacology, 2002.
Collaboration & Contact
I am open to collaborations in pediatric epilepsy, human tissue neurophysiology, and translational genomics.
- Email: John.P.Andrews@gmail.com
- Scholar: Google Scholar Profile
- ORCID: 0000-0002-8025-1525